Publications

Journal papers

Winzenrieth R., Humbert L., Di Gregorio S., Bonel E., Garcia M., Del Rio L. Effects of osteoporosis drug treatments on cortical and trabecular bone in the femur using DXA-based 3D modeling. Osteoporosis International, 2018, DOI:10.1007/s00198-018-4624-4
Humbert L., Winzenrieth R., Di Gregorio S., Thomas T., Vico L., Malouf J., del Río L. 3D Analysis of Cortical and Trabecular Bone From Hip DXA: Precision and Trend Assessment Interval in Postmenopausal Women. Journal of Clinical Densitometry 2018, in press, DOI:10.1016/J.JOCD.2018.05.001
Amy T Harding, Benjamin K Weeks, Steven L Watson, Belinda R Beck. The LIFTMOR-M (Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men) trial: protocol for a semirandomised controlled trial of supervised targeted exercise to reduce risk of osteoporotic fracture in older men with low bone mass. BMJ Open. 2017 Jun 12;7(6):e014951.
Lambert C, Beck BR, Harding AT, Watson SL, Weeks BK. A protocol for a randomised controlled trial of the bone response to impact loading or resistance training in young women with lower than average bone mass: the OPTIMA-Ex trial. BMJ Open. 2017 Sep 1;7(9):e016983.
Watson SL, Weeks BK, Weis LJ, Harding AT, Horan SA, Beck BR. High-Intensity Resistance and Impact Training Improves Bone Mineral Density and Physical Function in Postmenopausal Women With Osteopenia and Osteoporosis: The LIFTMOR Randomized Controlled Trial. J Bone Miner Res. 2017 Oct 4, 10.1002/jbmr.3284
L. Gifre, L. Humbert, A. Muxi, L. Del Rio, J. Vidal, E. Portell, A. Monegal, N. Guañabens, P. Peris. Analysis of the evolution of cortical and trabecular bone compartments in the proximal femur after spinal cord injury by 3D-DXA. Osteoporos Int., 2018 Jan;29(1):201-209. s00198-017-4268-9
Orduna G, Humbert L, Fonolla R, Romera J, Cos ML, Rial A, Nogués X, Diez-Perez A, Mellibovsky L. Cortical and Trabecular Bone Analysis of Patients With High Bone Mass From the Barcelona Osteoporosis Cohort Using 3-Dimensional Dual-Energy X-ray Absorptiometry: A Case-Control Study. J Clin Densitom. 2017 Jun 22. pii: S1094-6950(17)30065-3. doi: 10.1016/j.jocd.2017.05.012.
Clotet J, Martelli Y, Di Gregorio S, Del Río Barquero LM, Humbert L. Structural Parameters of the Proximal Femur by 3-Dimensional Dual-Energy X-ray Absorptiometry Software: Comparison With Quantitative Computed Tomography. J Clin Densitom. 2017 Jun 14. pii: S1094-6950(17)30017-3. doi: 10.1016/j.jocd.2017.05.002
Humbert L., Martelli Y., Fonolla R., Steghofer M., Di Gregorio S., Malouf J., Romera J., Del Rio Barquero L. 3D-DXA: Assessing the Femoral Shape, the Trabecular Macrostructure and the Cortex in 3D from DXA images. IEEE Trans Med Imaging. 2017 Jan;36(1):27-39.
Humbert L., Hazrati Marangalou J., Del Río Barquero LM., van Lenthe GH., van Rietbergen B. Technical Note: Cortical thickness and density estimation from clinical CT using a prior thickness-density relationship. Medical Physics 2016 Apr;43(4):1945. doi: 10.1118/1.4944501.
Whitmarsh T., Humbert L., del Río Barquero L. Miguel, Di Gregorio S., Frangi A. F. 3D Reconstruction of the Lumbar Vertebrae from Anteroposterior and Lateral Dual-energy X-ray Absorptiometry. Medical Image Analysis, 2013 May;17(4):475-87
Humbert L., Whitmarsh T., De Craene M., del Río Barquero L. Miguel, Frangi A. F. Comparison between Single and Multi-view Simulated DXA Configurations for Reconstructing the 3D Shape and Bone Mineral Density Distribution of the Proximal Femur. Medical Physics, 2012 Aug;39(8):5272-6
Whitmarsh T., Fritscher K., Humbert L., Miguel del Río Barquero L., Roth T., Kammerlander C., Blauth M., Schubert R., Frangi A. F. Hip Fracture Discrimination from Dual-energy X-ray Absorptiometry by Statistical Model Registration. Bone, 2012 Nov;51(5):896-901
Whitmarsh T., Humbert L., De Craene M., del Río Barquero L. Miguel, Frangi A. F. Reconstructing the 3D Shape and Bone Mineral Density Distribution of the Proximal Femur from Dual-energy X-ray Absorptiometry. IEEE Transactions on Medical Imaging, 2011 Dec;30(12):2101-14
L. Humbert, T. Whitmarsh, K. Fritscher, L. Miguel del Río Barquero, F. Eckstein, T. Link, R. Schubert, A. F. Frangi. Femoral Strength Prediction using a 3D Reconstruction Method from Dual-Energy X-rays Absorptiometry. IEEE International Symposium on Biomedical Imaging 2012, 1451-1454
T. Whitmarsh, K. Fritscher, L. Humbert, L. Miguel del Río Barquero, T. Roth, C. Kammerlander, M. Blauth, R. Schubert, A. F. Frangi. A Statistical Model of Shape and Bone Mineral Density Distribution of the Proximal Femur for Fracture Risk Assessment. Medical Imaging Computing and Computer Assisted Intervention (MICCAI), 2011, 14 (Pt 2):393-400.

Galgo Medical
Predictive Software for Safer Treatment

Galgo develops 3D medical image post-processing software solutions to add predictive value to personalized treatment strategies. Each patient is different and requires tailored treatment: personalized medication, surgical implants and interventional strategies. The increasing availability of high-quality patient images enables Galgo's algorithms and software to extract key clinical information to support clinical decision-making and planning and guidance of interventional procedures.

Galgo has focused on four medical disciplines:

Intra-cranial aneurysms, to plan, for each patient, the endovascular treatment with braided devices.

Epilepsy, to tailor the implantation of deep electrodes using complex 3D multimodal data.

Arrhythmias, to identify the arrhythmic substrate and to plan catheter ablation procedures from cardiac MRI.

Osteoporosis, to improve disease management by turning DXA images into 3D patient-specific models.

iso 13485
Galgo Medical SL has been certified by BSI to ISO 13485:2012 under certificate number MD 656038.

www.galgomedical.com